Description
Colchicine is a tricyclic alkaloid that can stay in circulation for 20 to 40 hours post intake. Leucocytes harbour maximum colchicine. It contains three hexameric rings termed A, B and C.Product ApplicationColchicine has been used:as an inhibitor of tubulin polymerization in bone-marrow-derived macrophagesfor the inhibition of in vitro neurite outgrowth in human neuronal cellsas microtubule destabilizer to induce peripheral neuropathy in induced pluripotent stem cell derived neurons (iPSC-Neurons)