Description
Casticin is one of the flavonoids present in the traditional Chinese medicineInula japonicaThunb. It is a polymethyl compound with three rings, a catechol moiety at ortho position, one double bond, two hydroxyl groups, and four methoxy groups. It has been isolated from the fruits, seeds, and leaves of variousVitexspecies.Casticin fromVitex trifoliais used to study its mechanisms of action as an antiiflammatory and anticancer agent via processes such as TRAIL-induced apoptosis, cell cycle arrest, ROS generation, and glutathione (GSH) depletion