Description
InformationCeMMEC1 HCl CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (IC50=0.9 µM).TargetsTAF1 (Cell-based assay) 1.8 µM(Kd)In vitroCeMMEC1 only bound BRD4 very weakly but it shows high affinity for the bromodomains of CREBBP, EP300, BRD9 and the second bromodomain of TAF1.Cell Research(from reference)Cell lines:REDS3 cells Concentrations:10 µM Incubation Time:24 h