Description
PLX7922, a RAF inhibitor, can bind with BRAF V600E. PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell linesIn VitroPLX7922 (1-1000 nM) inhibits pERK in BRAF V600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:RAF