Description
TMX-4113 is a degrader of phosphodiesterase 6D ( PDE6D ) and casein kinase 1α ( CK1α ). TMX-4113 can be used for the research of cancer.Appearance:SolidIC50& Target:PDE6D CK1αIn Vitro:TMX-4113 (compound 21; 1 µM; 4 h) shows a high degradation preference for PDE6D and CK1α in MOLT4 cells. TMX-4113 (0 nM, 40 nM, 200 nM, 1µM; 4h) induces degradation of PDE6D in MOLT4 cells. TMX-4113 (0 nM, 40 nM, 200 nM, 1µM; 4h) degrades over 5Biological Activity:TMX-4113 is a degrader of phosphodiesterase 6D ( PDE6D ) and casein kinase 1α ( CK1α ). TMX-4113 can be used for the research of cancer