XAV-939 from Aladdin Scientific

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Aladdin Scientific for
XAV-939

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Description

XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM, regulates axin levels and does not affect CRE, NF-κB or TGF-β.A potent inhibitor of beta-catenin, TNKS1, and TNKS2