Description
Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 29.34 µM in HepG2 cells. Ginsenoside Rg6 also exhibits apoptosis -inducing effect.In VitroGinsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC 50 of 25.12±1.04 µM in SK-Hep1 cells, consistent with the data from HepG2 cells. Ginsenoside Rg6 exhibits obvious anti-proliferative and apoptosis-inducing effects when it is applied to JK cells in vitro. Ginsenoside Rg6 blocks S arrest in the cell cycle. CCK-8 method shows that after Ginsenoside Rg6 is used, several groups with different concentrations obviously inhibits JK cell proliferation in human lymphocytoma, with evident dose dependency. Based on IC 50, the median inhibitory concentration of Ginsenoside Rg6 is 83.08 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:NF-κB:25.12 µM (IC:50:, in SK-Hep1 cell):NF-κB:29.34 µM (IC:50:, in HepG2 cell):Apoptosis