Duocarmycin TM from Aladdin Scientific

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Duocarmycin TM

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Description

Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA.In VitroDuocarmycin TM (60 µM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: BJAB and WSU-DLCL2 cells Concentration: 60 µM Incubation Time: 4 days Result: Inhibited the proliferation of tumor cells with IC 50 values of 0.153 µM and 0.079µM for BJAB and WSU-DLCL2 cells, respectively.Form:SolidIC50& Target:Duocarmycins