Description
GS-626510 is a potent, and orally active BET family bromodomains inhibitor, with K d values of 0.59-3.2 nM for BRD2/3/4, with IC 50 values of 83 nM and 78 nM foe BD1 and BD2, respectivelyForm:SolidIC50& Target:BRD2 0.59-2.5 nM (Kd) BRD3 0.65-0.66 nM (Kd) BRD4 1.3-3.2 nM (Kd) BD1 83 nM (IC 50 ) BD2 78 nM (IC 50 )