K-Ras G12C-IN-4 from Aladdin Scientific

K-Ras G12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRAS G12C.In VitroK-Ras G12C-IN-4 (4 hours) exhibits IC 50 =0.219 µM for inhibition of MAPK signaling (p-ERK) in MIA PaCa-2 cells. K-Ras G12C-IN-4 (72 hours) translates to a 0.067 µM IC 50 for inhibition of cellular viability in a CellTiter-Glo experiment in MIA PaCa-2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid