Description
MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor.Appearance:SolidIC50& Target:SIRT5In Vitro:MC3482 inhibits sirtuin5. 50 µM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-overBiological Activity:MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor