Description
InformationHS-27 is a fluorescently-tethered Hsp90 inhibitor that assays surface Hsp90 expression on intact tissue specimens. HS-27 consists of the core elements of SNX-5422 (Hsp90 inhibitor) and a fluorescein derivative (fluorescein isothiocyanate or FITC) via a PEG linker. HS-27 is potentially used in a see-and-treat paradigm in breast cancer