Calpain Inhibitor XII from Aladdin Scientific

Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 (K:i:= 19 nM). Calpain Inhibitor XII has been shown to inhibit calpain-2 (K:i:= 120 nM) and human cathepsin B (K:i:= 750 nM) only at higher concentrations. Calpain Inhibitor XII has been reported to induce neutrophile polarization and chemokinesis