Description
SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple agent-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 µg/ml and 0.08 to 5.48 µg/ml, respectivelyForm:SolidIC50& Target:gyrase B