Description
GSK-3 Inhibitor X is an acetoxime analog of BIO which acts as a selective GSK-3α/β inhibitor (IC:50:values are 0.01, 2.4, 4.3 and 63 µM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, respectively). GSK-3 Inhibitor X induces Wnt signaling and inhibits CD8+ T cell effector differentiation