Description
SHP836 is a SHP2 allosteric inhibitor, with an IC 50 of 12 µM for the full length SHP2In VitroSHP836 stabilizes the active conformation of SHP2, in which the catalytic site is blocked and no longer accessible to substrate. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 12 µM (SHP2)