Description
FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancersIn VitroFAPI-46 (1-24 h) robustly binds to human FAP in human FAP-expressing HT-1080 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoFAPI-46 (i.v.) shows improved ratios of tumor to liver, kidney, and brain uptake, resulting in an enhanced image contrast for PET imaging. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:fibroblast activation protein (FAP)