Description
Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replicationIn VitroDecanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2 ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell. ?\nDecanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL Concentration: 35 and 70 µΜ Incubation Time: 7 days Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition).Form:SolidIC50& Target:HIV-1 HIV-2