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Protein Biochemistry
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SC-43
SC-43 from MedChemExpress
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Citations:
(3)
Supplier Page
Supplier Page from
MedChemExpress for
SC-43
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Description
SC-43, a Sorafenib derivative, is a potent and orally active
SHP-1 (PTPN6)
agonist. SC-43 inhibits the phosphorylation of
STAT3
and induces cell
apoptosis
. SC-43 has anti-fibrotic and anticancer effects
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
SC-43
Company
MedChemExpress
Price
$275.00
Supplier Page
View Company Product Page
Catalog Number
HY-136657
Type
Chemical
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity
10 mM * 1 mL
Purity
99.01%
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (3)
(1)
Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer
Cancer communications (London, England)
April 1, 2023
Liu C, Wang X, Qin W, Tu J, Li C, Zhao W, Ma L, Liu B, Qiu H, Yuan X.
domain containing protein tyrosine phosphatase‐1 (SHP1) agonist SC43 were purchased from
MedChemExpress
(
HY‐136657
; Monmouth Junction, NJ, USA). Anti‐PD‐L1 was purchased from
BioXCell
(
BE0101
,
clone
10F.9G2, West Lebanon,
(2)
Targeting SHP-1-STAT3 signaling: A promising therapeutic approach for the treatment of cholangiocarcinoma
Oncotarget
September 12, 2017
Hu MH, Chen LJ, Chen YL, Tsai MS, Shiau CW, Chao TI, Liu CY, Kao JH, Chen KF.
(3)
Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
Scientific reports
May 11, 2017
Su TH, Shiau CW, Jao P, Yang NJ, Tai WT, Liu CJ, Tseng TC, Yang HC, Liu CH, Huang KW,
et al
.
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SC-43 from MedChemExpress
Supplier Page
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$275.00
Product Specs
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