Demecolcine from MedChemExpress

Product Specs
ItemDemecolcine
CompanyMedChemExpress
Price $132.00Supplier Page View Company Product Page
Catalog NumberHY-N0282
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL
Purity99.91%
Research AreaInflammation/Immunology; Cancer

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(1) ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback LoopAdvanced ScienceJanuary 5, 2026Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, et al.Yan. LP lab) were used as the polymeric components. Wedelolactone (WDL, ≥98%, MedChemExpress, cat. HY‐N0282) served as the payload. Hydrogen peroxide (H2O2, 30% w/w, Sigma), LPS (Sigma), DMEM, FBS, and penicillin‐streptomycin

(2) Machine learning identified extrachromosomal DNA-related 12 gene signatures to predict cancer immunotherapy responseCancer Cell IntDecember 18, 2025Yan Ju, Jingwei Zhang, Jiaming Deng, Xingyuan Wu, Haotian Yang, Changyu Tao, Xiao LiS1. Fluorescence in situ hybridization (FISH) Cell lines were treated with 10 ng/ml colcemid (MCE, HY-N0282) for 4 h. The cells were resuspended in 0.075 M KCl at 37 °C for 20 min and fixed using Carnoy’s fixative

(3) Establishing Bovine Embryonic Stem Cells and Dissecting Their Self-Renewal MechanismsInt J Mol SciApril 9, 2025Ningxiao Li, Zhen Yang, Yue Su, Wei Ma, Jianglin Zhao, Xiangyan Wang, Wenjing Wan, Shengcan Xie, Heqiang Li, Ming Wang, et al.perform karyotyping on various bESC lines, the cells were initially exposed to 10 μg/mL Demecolcine (MCE, HY-N0282) for 3 h at 37 °C. After this treatment, the cells were collected through trypsinization. Subsequently,

(4) Nuclear Overexpression of SAMHD1 Induces M Phase Stalling in Hepatoma Cells and Suppresses HCC Progression by Interacting with the Cohesin ComplexAdvanced ScienceDecember 16, 2024Juntang Shao, Wei Wang, Shiyu Li, Guangfa Yin, Lili Han, Xinyu Wang, Meng Cai, Tao Yang, Ying Wang, Wenyan Qu, et al.and are listed in Figure 5A. Metaphase Spread Assay Cells were treated with 100 ng ml−1 Colcemid (HY‐N0282, MCE) for 1.5 h to induce M phase arrest, then collected and resuspended in 0.075 mM KCl solution at

(5) Discovery and engineering of colchicine alkaloid biosynthesisNatureAugust 1, 2020Nett RS, Lau W, Sattely ES.

(6) Colcemid-induced apoptosis of cultured human glioma: electron microscopic and confocal laser microscopic observation of cells sorted in different phases of cell cycleCytometryApril 1, 1998Tsuchida T, Yoshimura K, Shirayama Y, Kawamoto K.

(7) An improved method for cytogenetic analysis of meiotic aneuploidy in rodent and frog spermatocytesMutation researchDecember 1, 1990Risley MS, Saccomanno CF, Pohorenec GM.

(8) Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoidsJournal of medicinal chemistryFebruary 1, 1990Muzaffar A, Brossi A, Lin CM, Hamel E.

(9) [Experimental studies on viral etiology of Epstein-Barr (EBV) in nasopharyngeal carcinoma (NPC):establishment of EBV infection on human epithelial derived from nasopharyngeal tissue (author's transl)]Nihon Jibiinkoka Gakkai kaihoFebruary 20, 1979Takimoto T.

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Demecolcine from MedChemExpress

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Demecolcine from MedChemExpress

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