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Protein Biochemistry
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2-NP
2-NP from MedChemExpress
Be the first to write a review!
Citations:
(9)
Supplier Page
Supplier Page from
MedChemExpress for
2-NP
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Description
2-NP is a selective enhancer of
STAT1
transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
2-NP
Company
MedChemExpress
Price
$77.00
Supplier Page
View Company Product Page
Catalog Number
HY-W013523
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.55%
Type
Chemical
Research Area
Infection; Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (9)
(1)
Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer
Molecular Cancer
February 10, 2026
Zhaohui Jiang, Yongting Liu, Peng Zhang, Jiang Fei, Kailing Wang, Yin Li, Xiangyang Zhang, Changjing Cai, Yihong Chen, Yinghui Peng,
et al.
sodium (DSS, #
HY-116282
),
Dynasore
(#
HY-15304
),
Pitstop 2
(#
HY-115604
),
EIPA
(#
HY-101840
), and
2-NP
(#
HY-W013523
) were purchased from
MCE
. An anti-mouse PD-L1 (B7-H1)-
InVivo
antibody (#A2115) was acquired from
Selleck
.
(2)
PLSCR1 Regulates the Physiology of Fibroblast-Like Synoviocytes via Modulating the STAT1 Signaling Pathway
Immun Inflamm Dis
October 27, 2025
Tianhua Chen, Jiaojiao Wang
cell culture medium
, and cells were incubated for 48 h before downstream analysis. The STAT1 enhancer (2‐NP,
HY‐W013523
) was obtained from
MedChemExpress
. Following siRNA
transfection
, cells were treated with the
2‐NP
(5
(3)
A small-molecule enhancer of STAT1 affects herpes simplex keratitis prognosis by mediating plasmacytoid dendritic cells migration through CXCR3/CXCL10
International immunopharmacology
February 6, 2025
Wang Y, Mao J, Yang K, Deng Q, Gao Y, Yan Y, Yang Z, Cong Y, Wan S, Yang W,
et al
.
(4)
Up-regulated Lnc BTU promotes the production of duck plague virus DNA polymerase and inhibits the activation of JAK-STAT pathway to facilitate duck plague virus replication
Poultry science
December 1, 2024
Luo N, Cheng A, Wang M, Chen S, Liu M, Zhu D, Wu Y, Tian B, Ou X, Huang J,
et al
.
China).
Cidofovir
(
HY-17438
), MG132,
Bafilomycin A1
,
Chloroquine
(CQ),
RO8191
(
HY-W063968
) and
2-NP
(
HY-W013523
) all purchased from (
MCE
, China). RNA Extraction and
Quantitative Real-Time PCR
RNA was extracted
(5)
Single-cell analysis of the survival mechanisms of fratricidal CAR-T targeting of T cell malignancies
Molecular Therapy - Nucleic Acids
June 11, 2024
Hui Hu, Ling Tang, Yuyan Zhao, Jiali Cheng, Mei Huang, Yong You, Ping Zou, Qian Lei, Xiaojian Zhu, An-Yuan Guo
regulation in CD44v6 CAR-
T cells
CD44v6 CAR-
T cells
were pretreated with 45 μmol/L
2-NP
(
MedChemExpress
,
HY-W013523
) for 1 h and then treated with 10 ng/mL
recombinant human IFN-γ
(
PeproTech
, cat. no. 10773-476) for
(6)
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3
Cell Communication and Signaling
May 10, 2024
Yan-Fei Wei, Xue Li, Meng-Ran Zhao, Si Liu, Li Min, Sheng-Tao Zhu, Shu-Tian Zhang, Si-An Xie
cefsulodin sodium (IC2530) were purchased from Solarbio (Beijing, China).
Fludarabine
(
HY-B0069
),
2-NP
(
HY-W013523
),
Maraviroc
(
HY-13004
), SB203580 (
HY-10256
), and
Upadacitinib
(
HY-19569
) were purchased from
MCE
(USA).
(7)
A Natural Peptide from A Traditional Chinese Medicine Has the Potential to Treat Chronic Atrophic Gastritis by Activating Gastric Stem Cells
Advanced Science
May 1, 2024
Ke Li, Xiuying Ma, Zihao Li, Ya Liu, Guiyan Shen, Zecheng Luo, Dong Wang, Li Xia, Zhengting Wang, Ming Tian,
et al.
and 5). For Stat1 and MEK1 agonist studies,
organoid
cultures were treated with
2‐NP
(45 µm,
MCE
, #
HY‐W013523
) and PAF‐C16 (1 µm,
MCE
, #
HY‐108635
) to substitute EGF. ELISA
Assay
for EGF‐EGFR Binding Affinity EGF
(8)
A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells
Cancer research
February 1, 2007
Lynch RA, Etchin J, Battle TE, Frank DA.
(9)
Localization of 3H-proline, 35S-sulfate and 3H-glucosamine in rat cornea following epithelial removal: epithelio-stromal interaction
Japanese journal of ophthalmology
January 1, 1989
Nakayasu K.
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2-NP from MedChemExpress
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$77.00
Product Specs
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