Sulforaphane from MedChemExpress

Product Specs
ItemSulforaphane
CompanyMedChemExpress
Price $38.00Supplier Page View Company Product Page
Catalog NumberHY-13755
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.75%
TypeChemical
Research AreaInflammation/Immunology; Cancer

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(1) Sulforaphane Alleviates Zearalenone-Induced Oxidative Stress in Bovine Mammary Epithelial CellsAnimals (Basel)May 25, 2026Yurong Fu, Tingting Liu, Peng Peng, Xi Chen, Siwei Wang, Shuang Liang, Shaoqing Shi, Chuanqi Wang, Kun WangReagents Zearalenone (purity ≥ 99%) was purchased from Selleck Chemicals (S5676, Houston, TX, USA). Sulforaphane (HY-13755, purity ≥ 98%) and the Nrf2 inhibitor ML385 (Cat. No. HY-100523) was obtained from MedChemExpress (South

(2) Sulforaphane Ameliorates High-Glucose-Induced Damage in a Diabetic Foot Ulcer Cell Model by Activating the Nrf2 Pathway to Improve Mitochondrial Function and Suppress InflammationBiomedicinesApril 27, 2026Xiao Chen, Zhimin Yin, Rui Jiao, Hui Han, Liangcai Yuan, Jie Zhoumake its osmotic pressure consistent with that of the HG (30 mmol/L D-glucose) group. Sulforaphane (HY-13755) was obtained from MedChemExpress (Monmouth Junction, NJ, USA) and was meticulously prepared by initially

(3) Sulforaphane alleviates hepatocyte pyroptosis via activating Nrf2-HO-1 signaling during septic acute liver injuryFront PharmacolOctober 16, 2025Shiying Xie, Min Liu, Lei Chen, Yincai Xie, Li Liu, Weina Chen, Huanwen Huang(n = 6 per group): Control, LPS (cat# L2630, Sigma, Saint Louis, United States) and LPS + SFN (cat# HY-13755, MCE, Shanghai, China). Mice were intraperitoneally administered SFN (10 mg/kg/day) for 2 days before

(4) The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinomaTheranosticsAugust 16, 2025Rongrong Liu, Xinyan Li, Jiayi Xu, Liangwen Yan, Kailing Hu, Mengjiao Shi, Yinggang Zhang, Yaping Zhao, Yudan Fan, Gang Wang, et al.Deferoxamine mesylate (HY-B0988), 6-Aminonicotinamide (HY-136057), Polydatin (HY-17589A), Sulforaphane (HY-13755), Vorinostat (HY-10221), Trichostatin A (HY-15144) and A-485 (HY-107455) were sourced from MCE. Hepatocellular carcinoma

(5) Increased ROS levels activate AMPK-ULK1-mediated mitophagy to promote pseudorabies virus replicationVet ResJuly 21, 2025Yuan Zhao, Xiaoyi Qi, Zhenbang Zhu, Wenqiang Wang, Wei Wen, Xiangdong LiDorsomorphin (MCE, HY-13418A), MCU-i4 (TargetMol, T9031), Rhod-2,AM (Yeasen, 40776ES50), Sulforaphane (MCE, HY-13755). Antibodies used were as follows: GAPDH (CST, 5174), COX4 (CST, 4850), SQSTM1/P62 (CST, 8025), LC3B

(6) Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1Journal of Advanced ResearchJuly 14, 2025Lin-Tao Xu, Qing-Tong Han, Zhen-Peng Xu, Xiao-Ning Wang, Hua Zhang, Tao Shenurate (MSU, HY-B2130A), pronase E (HY-114158), cycloheximide (CHX, HY-12320), and sulforaphane (SF, HY-13755) were purchased from MedChemExpress (Monmouth Junction, NJ, USA). Tert-butyl hydroquinone (TBHQ, PHR3512),

(7) PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular CarcinomaAdvanced ScienceMay 23, 2025Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin XiaHY‐16658), Necrosulfonamide (Necro; HY‐100573), MG‐132 (HY‐13259), TBHQ (HY‐100489), and Sulforaphane (HY‐13755) were purchased from MedChemExpress (New Jersey, USA). Ferostatin‐1(Fer‐1; S7243), MK‐2206 2HCl (S1078),

(8) Benzyl isothiocyanate provokes senolysis by targeting AKT in senescent IPF fibroblasts and reverses persistent pulmonary fibrosis in aged miceFront PharmacolMay 2, 2025Rui Wang, Fan Yang, Ying Liu, Meiting Peng, Lu Yu, Qinhui Hou, Yuan Liu, Zhenshun Chenghuman lung fibroblasts at passage 12 were stimulated with different ITCs, including SFN (MCE, cat#: HY-13755), iberin (MCE, cat#: HY-101413), 4-pentenyisothiocyanate (MCE, cat#: HY-W269799) and BITC (MCE, cat#:

(9) Insights from Metabolomic and Transcriptomic Analyses into Sulforaphane's Protective Mechanism Against Deoxynivalenol Toxicity via Spermine RegulationToxins (Basel)April 3, 2025Yeyi Xiao, Jianliang Wu, Menke Feng, Jie Wang, Lele Qi, Chao Xu, Haifei Wang, Wenbin BaoPribolab (Qingdao, China). Spermine (purity: ≥99.81%, HY-B1777) and sulforaphane (SFN, purity: 99.75%, HY-13755) were purchased from MedChemExpress (MCE, Shanghai, China). 5.2. Cell Treatment IPEC-J2 cells were

(10) Analysis of ferroptosis-related genes in cerebral ischemic stroke via immune infiltration and single-cell RNA-sequencingBMC medical genomicsFebruary 11, 2025Fan W, Zheng J, Jiang F.inserting an intraluminal filament. One technician performed every surgery. After the dissolution of SFN (HY-13755, MCE) in dimethylsulfoxide (DMSO, < 2%), the mixture was given into mice of the SFN + tMCAO and V +

(11) Effect of Media Composition and Oxygen Tension on Cellular Stress Response and Nrf2 Activation in HepG2ARE CellsAntioxidants (Basel)January 24, 2025Rutt Taba, Marie Põlluaed, Karin Tein, Marju Puurand, Tuuli Käämbre, Anton TerasmaaMTT and Nrf2 activation, 200 µM to measure GSH and MDA levels; (6) sulforaphane (MedChemExpress, Cat# HY-13755)—0.39 µM to 200 µM for viability and Nrf2, 50 µM for GSH and MDA measurement; and (7) bardoxolone (RTA-402

(12) Sulforaphane alleviates hepatocyte pyroptosis via activating Nrf2-HO-1 signaling during septic acute liver injuryFrontiers in pharmacologyJanuary 1, 2025Xie S, Liu M, Chen L, Xie Y, Liu L, Chen W, Huang H.(n = 6 per group): Control, LPS (cat# L2630, Sigma, Saint Louis, United States) and LPS + SFN (cat# HY-13755, MCE, Shanghai, China). Mice were intraperitoneally administered SFN (10 mg/kg/day) for 2 days before

(13) Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosisIran J Basic Med SciJanuary 1, 2025Daoyuan Lv, Laping Chu, Yuan Du, Chunqing Li, Neng Bao, Yuqing Su, Gang Wang, Yanlie Zheng, Yafen Yumanner. Treatment, groupings, and sample collection SFN, which was obtained from MedChemExpress LLC (#HY-13755, Shanghai, China), was dissolved in 10% DMSO+40% PEG300+5% Tween-80+45% normal saline. PHN rats were

(14) Sulforaphane regulates AngII-induced podocyte oxidative stress injury through the Nrf2-Keap1/ho-1/ROS pathwayRenal FailureDecember 31, 2024Wen Luspecies (ROS) detection kits were obtained from Beyontime (S0033S). Sulforaphane was sourced from MCE (HY-13755), the Cell Counting Kit-8 (CCK-8) was purchased from Biosharp, and the electrophoresis gel imaging analysis

(15) Protocatechuic acid relieves ferroptosis in hepatic lipotoxicity and steatosis via regulating NRF2 signaling pathwayCell Biology and ToxicologyNovember 26, 2024Yetong Feng, Mengjiao Shi, Yi Zhang, Xinyan Li, Liangwen Yan, Jiayi Xu, Chenyue Liu, Miaomiao Li, Fengyun Bai, Fenyue Yuan, et al.metabolic diseases. Materials and methods Chemicals and antibodies Protocatechuic acid (HY-N0294), sulforaphane (HY-13755), erastin (HY-15763), sorafenib (HY-10201), and palmitic acid (HY-N0830) were purchased from MedChemExpress

(16) Sulforaphane regulates AngII-induced podocyte oxidative stress injury through the Nrf2-Keap1/ho-1/ROS pathwayRen FailOctober 17, 2024Wen Luspecies (ROS) detection kits were obtained from Beyontime (S0033S). Sulforaphane was sourced from MCE (HY-13755), the Cell Counting Kit-8 (CCK-8) was purchased from Biosharp, and the electrophoresis gel imaging analysis

(17) Sulforaphane enhanced muscle growth by promoting lipid oxidation through modulating key signaling pathwaysBioscience ReportsJuly 31, 2024Rui Zhang, Suqin Chen, Feng Zhao, Wei Wang, Dayu Liu, Lin Chen, Ting Bai, Zhoulin Wu, Lili Ji, Jiamin ZhangSPF C57BL/6J mice, 4 weeks old, were purchased from Chengdu Dossy Experimental Animals Co., LTD. SFN (HY-13755, MedChemExpress) was dissolved in dimethyl sulfoxide (DMSO) and subsequently diluted with phosphate-buffered

(18) Sulforaphane enhanced muscle growth by promoting lipid oxidation through modulating key signaling pathwaysBiosci RepJuly 3, 2024Rui Zhang, Suqin Chen, Feng Zhao, Wei Wang, Dayu Liu, Lin Chen, Ting Bai, Zhoulin Wu, Lili Ji, Jiamin ZhangSPF C57BL/6J mice, 4 weeks old, were purchased from Chengdu Dossy Experimental Animals Co., LTD. SFN (HY-13755, MedChemExpress) was dissolved in dimethyl sulfoxide (DMSO) and subsequently diluted with phosphate-buffered

(19) NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammationScientific reportsMarch 4, 2024Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, et al.intraluminal filament. One technician was responsible for performing all operations. Sulforaphane (SFN, HY-13755, MCE) was dissolved within dimethylsulfoxide (DMSO, < 2%). For the SFN + tMCAO and V + tMCAO groups,

(20) Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumorsNature communicationsSeptember 18, 2023Wang X, Su S, Zhu Y, Cheng X, Cheng C, Chen L, Lei A, Zhang L, Xu Y, Ye D, et al.were then co-cultured with luciferase-expressing tumor cells. To test the function of NRF2, SFN (MCE, HY-13755, 10 μM) was added to the co-culture system. To test the function of cytokines, the supernatant was collected

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Sulforaphane from MedChemExpress

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Sulforaphane from MedChemExpress

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