LP-922056 from MedChemExpress | Biocompare.com

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LP-922056

Description

LP-922056 is an orally active, highly potent Notum Pectinacetylesterase inhibitor with EC₅₀s of 21 nM, 55 nM in human and mouse cellular assay, respectively. LP-922056 significantly increases midshaft femur cortical bone thickness in mice and rats

Product Specs
ItemLP-922056
CompanyMedChemExpress
Price $97.00Supplier Page View Company Product Page
Catalog NumberHY-131034
Quantity10 mM * 1 mL
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.63%
Research AreaOthers

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(1) NOTUM inhibition increases endocortical bone formation and bone strengthBone researchJanuary 1, 2019Brommage R, Liu J, Vogel P, Mseeh F, Thompson AY, Potter DG, Shadoan MK, Hansen GM, Jeter-Jones S, Cui J, et al.

(2) Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum PectinacetylesteraseBioorganic & medicinal chemistry lettersMarch 15, 2016Tarver JE Jr, Pabba PK, Barbosa J, Han Q, Gardyan MW, Brommage R, Thompson AY, Schmidt JM, Wilson AGE, He W, et al.

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