IDH1 Inhibitor 2 from MedChemExpress

Product Specs
ItemIDH1 Inhibitor 2
CompanyMedChemExpress
Price $1,163.00Supplier Page View Company Product Page
Catalog NumberHY-128661
Quantity10 mM * 1 mL
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.40%
Research AreaMetabolic Disease

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(1) A niche-dependent redox rheostat regulates epithelial stem cell fateNature CommunicationsNovember 28, 2025Xi Chen, Krishnan Raghunathan, Bin Bao, Elsy Ngwa, Andrew Kwong, Zhongyang Wu, Stephen Babcock, Clara Baek, George Ye, Anoohya Muppirala, et al.Dimethyl α-Ketoglutarate (3 mM, Sigma, 349631), or IDH1 inhibitor 2(compound 13, 2.5 mM, Medchemexpress, HY128661). For the stimulation with different niche factors, 24 hrs after seeding, primary epithelial cells were

(2) Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastomaNature CommunicationsNovember 25, 2025Bethany Veo, Dong Wang, John DeSisto, Angela Pierce, Breauna Brunt, Pradeep Chandra Bompada, Andrew Donson, Andrew Goodspeed, Kiara Smart, Nicholas Foreman, et al.done using the comparative Ct method. Compounds IDH305 (HY-104036), IDH1 inhibitor 2 (compound 13) (HY-128661), GSK321 (HY-18888) were all obtained from MedChemExpress. Chemical compounds were diluted in dimethylsulfoxide

(3) SKP2 ubiquitylation modifies IDH1 to regulate hepatoblastoma cell cycle and glucose metabolismBMC CancerAugust 11, 2025Pengxiang Yu, Jiarong Li, Wei Feng, Tao Lei, Wen Jia, Yun He, Yang BiSKP2 inhibitors(Selleck, S8652, 10mM (1mL in DMSO), China) as well as IDH1 inhibitors (MedchemExpress, HY-128661, 10mM (1mL in DMSO), USA)to treat the cells. The SKP2 inhibitor and IDH1 inhibitor stock solutions were

(4) Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastomaResearch SquareDecember 13, 2024Bethany Vibhakar, Bethany Wang, Dong DeSisto, Angela DeSisto, Angela Vibhakarconfirmed by qRT-PCR and western blot. Compounds. IDH305 (HY-104036), IDH1 inhibitor 2 (compound 13) (HY-128661), GSK321 (HY-18888) were all obtained from MedChemExpress. Chemical compounds were diluted in dimethylsulfoxide

(5) Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315Journal of medicinal chemistryAugust 9, 2018Jakob CG, Upadhyay AK, Donner PL, Nicholl E, Addo SN, Qiu W, Ling C, Gopalakrishnan SM, Torrent M, Cepa SP, et al.

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IDH1 Inhibitor 2 from MedChemExpress

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IDH1 Inhibitor 2 from MedChemExpress

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