Azoxymethane from MedChemExpress

Product Specs
ItemAzoxymethane
CompanyMedChemExpress
Price $332.00Supplier Page View Company Product Page
Catalog NumberHY-111375
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Format135 mM * 500 µL in Water
Purity≥99.0%
TypeChemical
Research AreaCancer

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(1) Atorvastatin promotes lipid catabolism in colorectal cancer via FDFT1‒mediated inhibition of the PI3K/AKT pathwayCell Communication and SignalingMarch 23, 2026Jiale Xu, Xiaoyu Qin, Longying Xiong, Cheng Zhao, Dan Ge, Yanping Wu, Yixuan Shen, Mengli Yang, Bihan Shen, Min Chen, et al.group (ATST). The MODEL and ATST groups of mice received an intraperitoneal injection of AOM (10 mg/kg; HY‒111375, MCE, P.R.China). One week later, DSS (0216011080, Tuoran Biotech, Shanghai, P.R.China) was administered

(2) Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular trapsNature CommunicationsFebruary 3, 2026Banglun Pan, Yuxin Yao, Zhu Zhang, Dongjie Ye, Hao Wu, Xinyu Zhang, Xiaoqian Wang, Nanhong Tangtimes.Chemical induction of CRC model: Mice received an intraperitoneal injection of AOM (10 mg/kg, HY-111375, MedChemExpress) and were given regular water for 14 d, followed by 7 d of 2.5% DSS (HY-116282C, MedChemExpress)

(3) FTO-mediated m6A demethylation of CSF3 suppresses NETosis via downregulation of RLN2 expression in colorectal cancerCell Biology and ToxicologyJanuary 7, 2026Junfeng Xu, Jie Zhang, Ruoran Li, Shengxin Chen, Changwei Duan, Xianzong Ma, Xuexin Wang, Xinyan Liu, Lingyun Gu, Ke Meng, et al.University. After one week of adaptation, mice were intraperitoneal injected 12.5 mg/kg azoxymethane (AOM) (#HY-111375, MCE), and the mice were supported drinking water supplemented with 2.5% DSS (#HY-116282, MCE) after

(4) RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic targetCancer CommunicationsOctober 16, 2025Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, et al.intraperitoneal injection two or three times a week. For the spontaneous CRC mouse model, the azoxymethane (AOM) (HY‐111375, MedChemExpress)/dextran sodium sulfate (DSS) (#HY‐116282, MedChemExpress) and ApcMin model were employed

(5) The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8 + T cells in micemSystemsFebruary 18, 2025Dengxiong Hua, Qin Yang, Xiaowei Li, Xuexue Zhou, Yingqian Kang, Yan Zhao, Daoyan Wu, Zhengrong Zhang, Boyan Li, Xinxin Wang, et al.time points. (ii) On day 1, the mice were weighed and noted, and AOM (10 mg/kg, MedChemExpress, Cat#: hy-111375) was intraperitoneally injected in the experimental group. (iii) Mice were fed with regular drinking

(6) Gut microbial and metabolomics profiles reveal the potential mechanism of fecal microbiota transplantation in modulating the progression of colitis-associated colorectal cancer in miceJournal of Translational MedicineNovember 15, 2024Qishi Song, Yongchao Gao, Kun Liu, Yukai Tang, Yichun Man, Haijun Wuof antibiotics, mice were subjected to an intraperitoneal injection of one dose of 10 mg/kg of AOM (HY111375, MedChemExpress, NJ, USA). A week after the AOM injection, the mice were allocated at random into 5

(7) The association of appendectomy with prognosis and tumor-associated macrophages in patients with colorectal canceriScienceSeptember 20, 2024Gaixia Liu, Chenhao Hu, Jiangpeng Wei, Qixin Li, Jiaqi Zhang, Zhe Zhang, Penghong Qu, Zeyu Cao, Ruochen Wang, Gang Ji, et al.Bovine Serum Albumin,Solarbio,Cat#A8010 DNase,Roche,CAS#9003-98-9 dextran sulfate sodium,MP Biomedicals,CAS#0216011080 azoxymethane,MCE,CAS#HY-111375 Oxaliplatin,MCE,Cat #HY-17371 Gefitinib,MCE,Cat #HY-50895 Anti-Mouse PD-1 antibody,MCE,Cat #HY-P99144 ,, Critical

(8) Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single-cell sequencing dataScientific ReportsAugust 5, 2024Wanhui Wei, Yuanyuan Lu, Mengjiao Zhang, JinKun Guo, Heng Zhang37 °C in a humidified incubator with 5% CO2. Lipopolysaccharides (LPS; HY-D1056), Azoxymethane (AOM; HY-111375) and Dextran sulfate sodium (DSS; HY-116282C) were purchased from MedChemExpress (MCE, USA). Spermine

(9) NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesisEBioMedicineNovember 1, 2020Wei M, Ma Y, Shen L, Xu Y, Liu L, Bu X, Guo Z, Qin H, Li Z, Wang Z, et al.colitis-associated colorectal cancer, we used the combination of the carcinogen azoxymethane (AOM, MedChemExpress, hy-111375) with repeated treatment with DSS in drinking water. Mice were treated with an intraperitoneal injection

(10) Colon carcinogenesis in wild type and immune compromised mice after treatment with azoxymethane, and azoxymethane with dextran sodium sulfateMolecular carcinogenesisJuly 1, 2016Whetstone RD, Wittel UA, Michels NM, Gulizia JM, Gold B.

(11) Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in miceChemical research in toxicologyApril 21, 2014Megaraj V, Ding X, Fang C, Kovalchuk N, Zhu Y, Zhang QY.

(12) Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesisCancer researchJanuary 15, 2007Fichera A, Little N, Jagadeeswaran S, Dougherty U, Sehdev A, Mustafi R, Cerda S, Yuan W, Khare S, Tretiakova M, et al.

(13) Separation and properties of NAD+- and NADP+-dependent glyceraldehyde-3-phosphate dehydrogenases from Streptococcus mutansThe Journal of biological chemistryFebruary 25, 1979Crow VL, Wittenberger CL.

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Azoxymethane from MedChemExpress

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Azoxymethane from MedChemExpress

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