BMH-21 from MedChemExpress

Product Specs
ItemBMH-21
CompanyMedChemExpress
Price $46.00Supplier Page View Company Product Page
Catalog NumberHY-12484
Research AreaCancer
Purity99.25%
Quantity5 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeChemical

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(1) Dual RNA Polymerase I Inhibition with CX-5461 and BMH-21 Synergizes in Breast Cancer by Activating p53-Dependent StressbioRxivJanuary 16, 2026Jonathan Y. Chung, Kristen N. Nguyen, Bruce A. Knutson(Siegl et al., 2023). 3.2 Viability Assays and Synergy Determination CX-5461 (HY-13323) and BMH-21 (HY-12484) were purchased from MedChemExpress (Monmouth Junction, NJ). CX-5461 was dissolved in 50 mM sodium phosphate

(2) Pre-rRNAs control mitosis by maintaining chromosomal segregation through protecting SMC2 from AURKA-mediated phosphorylationCell Death & DiseaseNovember 7, 2025Shiqi Sun, Kunqi Su, Yang Jiang, Yuying Wang, Yang Hu, Chang Wang, Zhuochen Zhao, Chunfeng Zhang, Baocai Xing, Xiaojuan DuLI-COR (926-68071 and 926-32210). Actinomycin D (Act D, SBR00013) was purchased from Sigma. BMH-21 (HY-12484) and CX5461 (HY-13323) were purchased from MedChemExpress. TCS7010 (S1451) was purchased from Selleck.

(3) SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosisMolecular CellMarch 6, 2025Akane Ogawa, Keiichi Izumikawa, Sota Tate, Sho Isoyama, Masaru Mori, Kohei Fujiwara, Soyoka Watanabe, Takayuki Ohga, Ukhyun Jo, Daiki Taniyama, et al.Solution (100x),Nacalai Tesque,Cat# 09366-44 Actinomycin D,Sigma-Aldrich,A1410 BMH-21,MedChemExpress,HY-12484 LY2606368 (CHK1 inhibitor),Developmental Therapeutics Program (NCI/NIH),NSC#758257 Palbociclib (CDK4/6

(4) Ribosome biogenesis is essential for hemogenic endothelial cells to generate hematopoietic stem cellsDevelopmentNovember 1, 2024Di Liu, Haizhen Wang, Haifeng Chen, Xitong Tian, Yuqing Jiao, Chi Wang, Yuhui Li, Zongcheng Li, Siyuan Hou, Yanli Ni, et al.presence or absence of 50 nM CX-5461 (MCE, HY-13323), 50 nM CX-3543 (MCE, HY-14776) and 20 nM BMH-21 (MCE, HY-12484). After 6 days of co-culture, cells in each well were harvested for flow cytometry analysis and transplantation. Transplantation

(5) Real-time imaging of RNA polymerase I activity in living human cellsThe Journal of cell biologyJanuary 2, 2023Fu Y, Liu Y, Wen T, Fang J, Chen Y, Zhou Z, Gu X, Wu H, Sheng J, Xu Z, et al.validate the use of LiveArt for anticancer drug screening, available drugs, including BMH-21 (MCE, HY-12484), Cisplatin (MCE, HY-17394), CX-5461 (MCE, HY-13323; TargetMol, T2100), Doxorubicin (hydrochloride;

(6) The nucleolus as a polarized coaxial cable in which the rDNA axis is surrounded by dynamic subunit-specific phasesCurrent BiologyJune 1, 2021Alan M. Tartakoff, Lan Chen, Shashank Raghavachari, Daria Gitiforooz, Akshyasri Dhinakaran, Chun-lun Ni, Cassandra Pasadyn, Ganapati H. Mahabaeleshwar, Vanessa Pasadyn, John L. WoolfordRESOURCE,SOURCE,IDENTIFIER Chemicals,Chemicals,Chemicals Anisomycin,Sigma Chemical,A-9789 BMH-21,MedChemExpress,HY-12484/CS-3557 Cycloheximide,Sigma-Aldrich,C7698 Rapamycin,Millipore,553211 Thiolutin,"N. Belcher, Pfizer",lot

(7) DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage responseOncotargetJune 30, 2014Colis L, Peltonen K, Sirajuddin P, Liu H, Sanders S, Ernst G, Barrow JC, Laiho M.

(8) A targeting modality for destruction of RNA polymerase I that possesses anticancer activityCancer cellJanuary 13, 2014Peltonen K, Colis L, Liu H, Trivedi R, Moubarek MS, Moore HM, Bai B, Rudek MA, Bieberich CJ, Laiho M.

(9) Primary thalamic hemorrhage in a preterm infantPediatric neurologyMarch 1, 1987Weissman BM, Foster D, Baley JE.

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BMH-21 from MedChemExpress

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BMH-21 from MedChemExpress

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