MQAE from MedChemExpress

Product Specs
ItemMQAE
CompanyMedChemExpress
Price $60.00Supplier Page View Company Product Page
Catalog NumberHY-D0090
Quantity50 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.84%
TypeChemical
Research AreaOthers

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(1) Mitochondrial Fragmentation Induced by the CFTR Modulators Lumacaftor and Ivacaftor in Immortalized Cystic Fibrosis Cell LinesCellsOctober 15, 2025Camila Dib, Pablo A. Iglesias González, María de Los Ángeles Aguilar, Guillermo L. Taminelli, Tatiana Limpias Del Valle, Nadia E. Nuñez, Analía G. Karadayian, Tomás A. Santa-Coloma, Ángel G. Valdiviesoinhibitor cocktail (Cat. N° HY-K0010), MQAE (N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, Cat. N° HY-D0090), Nigericin (Cat. N° HY-127019) and phosphatase inhibitors (Cat. N° HY-K0022), were purchased from MedChemExpress

(2) Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium ElevationAdvanced ScienceJuly 18, 2025Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, et al.obtained by CLSM. Intracellular Cl− Measurement Intracellular Cl− concentration was measured using MQAE (HY‐D0090, MCE). Briefly, cells were incubated with 5 mm MQAE in Krebs‐Hepes solution for 30 min at 37 °C. After

(3) Chloride intracellular channel CLIC3 mediates fibroblast cellular senescence by interacting with ERK7Commun BiolJanuary 14, 2025Changjiao Luan, Yue Gao, Jun Zhao, Xiaohui Zhang, Chaofan Wang, Wentao Sun, Yucheng Li, Xinxing Yang, Jiaxiao Chen, Weili Liu, et al.Bleomycin sulfate (HY-17565) (1 µg/ml for in vitro studies and 1.875 mg/kg for in vivo studies), MQAE (HY-D0090) (10 µM), IAA-94 (HY-12693) (10 µM), CK2/ERK8-IN-1 (CK2) (HY-135906) (10 µM), and CCCP (HY-100941) (10

(4) LRRC8A drives NADPH oxidase-mediated mitochondrial dysfunction and inflammation in allergic rhinitisJournal of translational medicineNovember 16, 2024Meng L, Hao D, Liu Y, Yu P, Luo J, Li C, Jiang T, Yu J, Zhang Q, Liu S, et al.the intracellular chloride content, MQAE, a chloride-sensitive fluorescent probe, was used (5 Mm, #HY-D0090, Medchemexpress). Following the manufacturer's protocol, stimulated HNEpCs on slides were washed three

(5) Gut commensal metabolite rhamnose promotes macrophages phagocytosis by activating SLC12A4 and protects against sepsis in miceActa Pharmaceutica Sinica BJuly 1, 2024Dongping Li, Rongjuan Wei, Xianglong Zhang, Shenhai Gong, Meijuan Wan, Fangzhao Wang, Jiaxin Li, Meiling Chen, Ruofan Liu, Yantong Wan, et al.were then labelled with 10 mmol/L MQAE (N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide, Cat# HY-D0090, MCE, China) for 1 h in DMEM medium. Cells were then washed three times with Cl− containing buffer (HBSS)

(6) Sevoflurane-induced regulation of NKCC1/KCC2 phosphorylation through activation of Spak/OSR1 kinase and cognitive impairment in ischemia-reperfusion injury in ratsHeliyonJune 30, 2024Wang Y, Zhang Y, Yu W, Dong M, Cheng P, Wang Y.were diluted using PBS. Then, 100 μL of this suspension was mixed with 10 mM MQAE (MedChemExpress Cat# HY-D0090) and incubated at 37 °C for 10 min, following the method described by Perry et al. [30]. Flow cytometry

(7) Acacetin inhibits inflammation by blocking MAPK/NF-κB pathways and NLRP3 inflammasome activationFrontiers in pharmacologyJanuary 1, 2024Bu J, Mahan Y, Zhang S, Wu X, Zhang X, Zhou L, Zhang Y.5 min, the supernatant was transferred to a fresh 1.5 mL EP tube. An equal volume of 50 μL of MQAE (HY-D0090, MedChemExpress, United States) at a concentration of 10 μM was added to the supernatant, and the mixture

(8) Biphasic regulation of CFTR expression by ENaC in epithelial cells: The involvement of Ca2+-modulated cAMP productionFrontiers in Cell and Developmental BiologyAugust 30, 2022Fulei Wuchu, Xiyang Ma, Yanting Que, Junjiang Chen, Ye Chun Ruanon the coverslip were incubated with a Cl- sensitive fluorescent dye, MQAE (10 mM, MedChemExpress, HY-D0090) in Margo-Ringer buffer for 30 min at 37°C followed by washing and stabilizing for another 10 min. The

(9) Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca²⁺ Signaling in the Determination of Skeletal Muscle Development PotentialCellsApril 22, 2020Qiu K, Xu D, Wang L, Zhang X, Jiao N, Gong L, Yin J.collected using a 530/30 nm band-pass filter. N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide (MQAE, HY-D0090, MedChemExpress, South Brunswick, NJ, USA) was used to estimate the Cl− influx of cells. The fluorescence

(10) Two-photon chloride imaging using MQAE in vitro and in vivoCold Spring Harbor protocolsJuly 1, 2012Kovalchuk Y, Garaschuk O.

(11) Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescenceMicroscopy research and techniqueDecember 15, 2002Andersson C, Roomans GM.

(12) Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cellsThe American journal of physiologyDecember 1, 1994Koncz C, Daugirdas JT.

(13) [Lack of clarity in medical articles. Apropos of 1 case]Revista espanola de las enfermedades del aparato digestivoJune 1, 1989Lera Tricas JM.

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