Sumatriptan from MedChemExpress | Biocompare.com

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Sumatriptan

Description

Sumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC₅₀s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT_1D, 5-HT_1B and 5-HT_1F receptors, respectively. Sumatriptan can be used for migraine headache research

Product Specs
ItemSumatriptan
CompanyMedChemExpress
Price $88.00Supplier Page View Company Product Page
Catalog NumberHY-B0121B
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.96%
TypeChemical
Research AreaNeurological Disease

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(1) Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in miceCephalalgia : an international journal of headacheFebruary 1, 2010Bates EA, Nikai T, Brennan KC, Fu YH, Charles AC, Basbaum AI, Ptácek LJ, Ahn AH.

(2) Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activationBritish journal of clinical pharmacologyJanuary 1, 1999Razzaque Z, Heald MA, Pickard JD, Maskell L, Beer MS, Hill RG, Longmore J.

(3) Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headacheDrugsMay 1, 1992Dechant KL, Clissold SP.

(4) Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sitesEuropean journal of pharmacologyApril 12, 1989Peroutka SJ, McCarthy BG.

(5) Novel treatment for epistaxisIMJ. Illinois medical journalMarch 1, 1976Greenwood RD.

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