Description
An NRTI; reduces viral infectivity in HIV-1-infected HEK293T cells (EC50 = 0.063 nM); reduces viral replication in 2209-23 cells stably transfected with HCV 1b (EC50 = 24 nM); reduces viral load and the number of lung ground-glass opacities observed via chest X-ray in a rhesus macaque model of SARS-CoV-2 infection at 0.7 mg/kg