Description
An HDAC6 inhibitor (IC50 = 10 nM); selective for HDAC6 over HDAC1-5 (IC50s = 211-516 nM) and HDAC7, -8, -9, and -11 (IC50s = 137-812 nM); reduces the level of proteins involved in fibrosis, including collagen-1A1, α-SMA, and fibronectin, in human pulmonary fibroblasts at 10 µM