Description
A chromene with anti-juvenile hormone activity; inhibits juvenile hormone biosynthesis in isolated spontaneously active cockroach corpora allata at ≥1 mM; inhibits development of the corpus allatum in newly eclosed female milkweed bugs and causes allatal regression when applied 120 hours post-eclosion in normally developing females at 8 µg/cm2 as a coating in Petri dish; induces precocious metamorphosis in milkweed bug second-stage nymphs when applied as a coating to Petri dishes at 0.4 and 0.7 µg/cm2; inhibits ovarian development in various insects, including milkweed bugs, cotton stainers, apple maggots, and Mexican bean beetles; inhibits production of the trichothecene mycotoxin 3-ADON in F. graminearum (IC50 = 1.2 µM) without inhibiting fungal growth