PR-924 from MyBioSource.com

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PR-924

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Description

PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has Antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites