Description
KLS-13019 is a Cannabidiol-Derived Neuroprotective Agent with Improved Potency, Safety, and Permeability. (EC50=4nM; T1=7500). KLS-13019 was 50-fold more potent and 400-fold safer than cannabidiol and exhibited an in vitro profile consistent with improved oral bioavailability. KLS-13019 was only toxic at 300uM giving it a therapeutic index of 7500