Description
6alpha-hydroxy Paclitaxel is a primary metabolite of the anticancer compound paclitaxel, produced by the action of the cytochrome P450 isoform CYP2C8. The generation of 6alpha-hydroxy paclitaxel by CYP2C8 can be impacted by other drugs or dietary components that interefere with CYP2C8 activity, as well as by CYP2C8 genetic polymorphisms