Description
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21uM), DNAPK (IC50, 2.8uM), PI3Kalpha (IC50, 3.8uM), PI3Kbeta (IC50, 10.3uM), PI3Kgamma (IC50, 3uM) and PI3Kdelta (IC50, 0.73uM)