Description
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5). VGSC blocker-1 blocks INa peak currents 34.9% at 1 uM and inhibits cell invasion 0.3% at 1 uM in human breast cancer cell line MDA-MB-231, without affecting the cell viability