Description
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 ug/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 ug/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 ug/disc. It also induces cell death in HCT116 colorectal carcinoma cells