Description
A phenol with diverse biological activities; scavenges DPPH radicals, reduces the formation of TBARS, and inhibits xanthine oxidase in cell-free assays (IC50s = 20.17, 2, and 16.7 µM, respectively); cytotoxic to HT-29 cells (IC50 = 30 µg/ml); reduces paw edema and arthritic paw tissue homogenate levels of IL-1β, PGE2, LTB4, and NO in a mouse model of steam-killed M. tuberculosis-induced arthritis at 4 mg/kg; has been used as a precursor in the synthesis of, and is a metabolite of, safrole