Description
A PU.1 inhibitor (IC50 = 14 nM); long-term exposure reduces KSL-HSPC colony formation at 300 nM; decreases ovalbumin-induced reprogramming of isolated mouse neutrophils into antigen-presenting cells at 700 nM; decreases tumor growth, weight, and volume in a U87MG glioblastoma multiforme mouse xenograft model at 10 mg/kg per day