Description
A dopamine D2, D3, and D4 receptor antagonist (Kis = 0.7, 14, and 27 nM, respectively, in NIH3T3 cells expressing the human receptors); inhibits E. electricus AChE (Ki = 120 µM); is a histamine H1 receptor inverse agonist (IC50 = 794 nM); intraocular administration induces ocular hypotension in normotensive rabbits at 0.5% w/v