Zoledronic Acid from MedChemExpress

Product Specs
ItemZoledronic Acid
CompanyMedChemExpress
Price $96.00Supplier Page View Company Product Page
Catalog NumberHY-13777
Quantity50 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.91%
TypeChemical
Molecular Weight272.09
Molecule NameZoledronic Acid
FormulaC5H10N2O7P2
Research AreaMetabolic Disease; Cancer

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(1) Impaired function of Vγ9Vδ2 T cells in frail elderlyImmunity & AgeingJanuary 16, 2026Hui Li, Xiaxuan Li, Hangyu Chen, Zhanqun Yang, Mengzhu Zheng, Yuan Xue, Yingying Yan, Jian Lin, Xuan Lai, Long Chenfetal bovine serum (Gibco, 26010074). The PBMCs were then stimulated with 5 µM of Zoledronic acid (MCE, HY-13777) for the first three days and recombinant human interleukin-2 (Tonglihaiyuan, GMP-TL906-0050) at a concentration

(2) Chemical engineering of γδ T cells with cancer cell-targeting antibodies for enhanced tumor immunotherapyNational Science ReviewJune 27, 2025Long Chen, Bo Cheng, Zhanqun Yang, Mengzhu Zheng, Tianyu Chu, Pan Wang, Tianhui He, Yuan Xue, Houyi Ren, Liting Zheng, et al.26010074) at a density of (1–3) × 106 cells/mL. PBMCs were stimulated with 5 μM zoledronic acid (MCE, HY-13777) for the first 3 days and stimulated for 14 days with recombinant human interleukin-2 (T&L Biotechnology

(3) Aerobic exercise prevents renal osteodystrophy via irisin-activated osteoblastsJCI InsightJanuary 30, 2025Meng Wu, Huilan Li, Xiaoting Sun, Rongrong Zhong, Linli Cai, Ruibo Chen, Madiya Madeniyet, Kana Ren, Zhen Peng, Yujie Yang, et al.for 4 weeks. For in vivo drug treatment, mice were i.p. treated with 100 μg/kg of zoledronic acid (HY-13777, MedChemExpress) once per week and with 150 IU/kg per of calcitriol (17938, Sigma-Aldrich) once per

(4) Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localizationCommunications BiologyNovember 9, 2024Gang Wang, Tianchen Peng, Liang Chen, Kangping Xiong, Lingao Ju, Kaiyu Qian, Yi Zhang, Yu Xiao, Xinghuan Wangserum (FBS). The UM-UC-3 and HEK 293T cell lines were cultured in DMEM (containing 10% FBS). ZOL (Cat. #HY-13777), simvastatin (Cat. #HY-17502) and cholesterol (Cat. #HY-N0322A) were purchased from MCE. FPP (Cat.

(5) Oral Zoledronic acid bisphosphonate for the treatment of chronic low back pain with associated Modic changes: A pilot randomized controlled trialJournal of orthopaedic research : official publication of the Orthopaedic Research SocietyDecember 1, 2022Shea GKH, Zhang C, Suen WS, Cheung PWH, Cheung JPY, Maatta J, Karppinen J, Samartzis D.

(6) Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief reviewBMC cancerNovember 3, 2020Wang L, Fang D, Xu J, Luo R.

(7) Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-κB and JNK signalling pathwaysInternational journal of molecular medicineAugust 1, 2019Huang XL, Huang LY, Cheng YT, Li F, Zhou Q, Wu C, Shi QH, Guan ZZ, Liao J, Hong W.

(8) Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL AxisInternational journal of molecular sciencesMarch 22, 2019Kim HJ, Kim HJ, Choi Y, Bae MK, Hwang DS, Shin SH, Lee JY.

(9) Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitroMolecular medicine reportsJanuary 1, 2016Huang X, Huang S, Guo F, Xu F, Cheng P, Ye Y, Dong Y, Xiang W, Chen A.

(10) High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical propertiesClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 15, 2009Pozzi S, Vallet S, Mukherjee S, Cirstea D, Vaghela N, Santo L, Rosen E, Ikeda H, Okawa Y, Kiziltepe T, et al.

(11) Binding of 4-methylumbelliferyl alpha-d-mannopyranoside to dimeric and tetrameric concanavalin A: equilibria and kinetic study using temperature-jump relaxation of fluorescence quenching [proceeding]Archives internationales de physiologie et de biochimieFebruary 1, 1977Loontiens FG, Clegg RM, Jovin TM.

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Zoledronic Acid from MedChemExpress

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Zoledronic Acid from MedChemExpress

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