DM3 from MedChemExpress | Biocompare.com

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DM3

Description

DM3 (Maytansinoid DM3), a Maytansine (HY-13674) analog bearing disulfide or thiol groups, and is a tubulin inhibitor. DM3 a cytotoxic moiety of antibody-drug conjugates (ADCs)

Product Specs
ItemDM3
CompanyMedChemExpress
Price $781.00Supplier Page View Company Product Page
Catalog NumberHY-130080
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeChemical
Molecular Weight766.34
Molecule NameDM3
FormulaC37H52ClN3O10S
Research AreaCancer

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(1) High anti-tumor activity of a novel alpha-fetoprotein-maytansinoid conjugate targeting alpha-fetoprotein receptors in colorectal cancer xenograft modelCancer cell internationalApril 5, 2023Griffin P, Hill WA, Rossi F, Boohaker R, Stinson K, Sherman I.

(2) Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer TherapyMolecules (Basel, Switzerland)August 1, 2017Chen H, Lin Z, Arnst KE, Miller DD, Li W.

(3) Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol estersBrain researchSeptember 28, 2001Trotti D, Peng JB, Dunlop J, Hediger MA.

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