TCS PrP Inhibitor 13 from MedChemExpress

Description

TCS PrP Inhibitor 13, an antiprion agent, is a cellular prion protein (PrP^C) inhibitor. TCS PrP Inhibitor 13, as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor, shows an IC₅₀ value of 3 nM in both ScN2a and F3 cell lines. TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis

Product Specs
ItemTCS PrP Inhibitor 13
CompanyMedChemExpress
Price $105.00Supplier Page View Company Product Page
Catalog NumberHY-107662
FormulaC15H11N3O3
TypeChemical
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Quantity10 mM * 1 mL
Molecule NameTCS PrP Inhibitor 13
Research AreaInfection; Cancer
Molecular Weight281.27
Purity99.72%

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(1) Cellular prion protein (PrP^C) in the development of Merlin-deficient tumoursOncogeneNovember 2, 2017Provenzano L, Ryan Y, Hilton DA, Lyons-Rimmer J, Dave F, Maze EA, Adams CL, Rigby-Jones R, Ammoun S, Hanemann CO.

(2) New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulationJournal of medicinal chemistryOctober 18, 2007Kimata A, Nakagawa H, Ohyama R, Fukuuchi T, Ohta S, Doh-ura K, Suzuki T, Miyata N.

(3) Re: Standard treatments for pneumonia in Papua New GuineaPapua and New Guinea medical journalMarch 1, 1989Shann F.

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TCS PrP Inhibitor 13 from MedChemExpress

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TCS PrP Inhibitor 13 from MedChemExpress

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