Description
A STING activator (EC50 = 0.33 µM in a reporter assay using THP-1 human monocytes); increases IFN-β and IP-10 levels in the presence, but not absence, of cGAMP; reduces the viability of CT26 cells at 0.31-20 µM; reduces tumor growth in a CT26 mouse syngeneic model at 15 mg/kg when used in combination with 2’3’-cGAMP