ENPP1 Inhibitor 4e from Cayman Chemical

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ENPP1 Inhibitor 4e

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Description

An ENPP1 inhibitor (IC50 = 0.188 µM); inhibits ENPP1 in MDA-MB-231 cells (IC50 = 0.732 µM); selectively cytotoxic to 4T1 murine metastatic breast cancer cells (IC50 = 2.99 µM) over non-cancerous L-02 and 293T cells at 50 µM; increases serum levels of IFN-β in mice when administered at a dose of 0.5 mg/kg in combination with cGAMP