Description
A mitochondrial citrate transporter inhibitor; decreases the OCR in tumor spheres isolated from patients with NSCLC and inhibits the invasion of lung cancer stem cells in vitro; acts synergistically with cisplatin to reduce the viability of cisplatin-resistant patient-derived NSCLC cells at 50 µM; reverses increases in body weight, steatosis, and fasting blood glucose levels in a mouse model of high fat-diet induced NAFLD at 50 mg/kg