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Protein Biochemistry
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ACBI2
ACBI2 from MedChemExpress
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Citations:
(2)
Supplier Page
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MedChemExpress for
ACBI2
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Description
ACBI2 is a highly potent and orally active
VHL PROTAC
SMARCA2
degrader (
EC
50
: 7 nM), which selectively degrades
SMARCA2
with a
DC
50
value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
ACBI2
Company
MedChemExpress
Price
$300.00
Supplier Page
View Company Product Page
Catalog Number
HY-151623
Quantity
1 mg
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.76%
Type
Chemical
Molecular Weight
1063.17
Formula
C₅₇H₆₉BrFN₇O₅S
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (2)
(1)
Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
Cell Chemical Biology
December 19, 2024
Sasikumar Kotagiri, Nicholas Blazanin, Yuanxin Xi, Yanyan Han, Md Qudratullah, Xiaobing Liang, Yawen Wang, Poonam Pandey, Hira Mazhar, Truong Nguyen Lam,
et al.
S9612) and
Pomalidomide
(Cat#
S1567
) were purchased from
Selleck Chemicals
(Houston, TX).
ACBI2
(Cat#
HY-151623
), VT-107 (Cat#
HY-134957
) and Gen-1 (Cat#
HY-44012
) were purchased from
MedChemExpress
(South Brunswick
(2)
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Nature communications
October 10, 2022
Kofink C, Trainor N, Mair B, Wöhrle S, Wurm M, Mischerikow N, Roy MJ, Bader G, Greb P, Garavel G,
et al
.
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ACBI2 from MedChemExpress
Supplier Page
View Company Product Page
$300.00
Product Specs
Company Info
Citations
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