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Protein Biochemistry
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Ruxolitinib phosphate
Ruxolitinib phosphate from MedChemExpress
Be the first to write a review!
Citations:
(8)
Supplier Page
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MedChemExpress for
Ruxolitinib phosphate
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Description
Ruxolitinib phosphate (INCB018424 phosphate) is a potent
JAK1/2
inhibitor with
IC
50
s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ruxolitinib phosphate
Company
MedChemExpress
Price
$66.00
Supplier Page
View Company Product Page
Catalog Number
HY-50858
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
99.97%
Type
Chemical
Molecular Weight
404.36
Molecule Name
Ruxolitinib (phosphate)
Formula
C17H21N6O4P
Research Area
Cancer
Add to Compare List
MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (8)
(1)
JAK1/2 Inhibition Delays Cachexia and Improves Survival through Increased Food Intake
bioRxiv
October 25, 2025
Ezequiel Dantas, Anirudh Murthy, Jeshua Kim, Tanvir Ahmed, Mujmmail Ahmed, Tiffany Perrier, Shakti Ramsamooj, Isaac Nathoo, Lucas Kniess Debarba, Andre Lima Queiroz,
et al.
rate of IL-6 infusion was 1μL/hour at a concentration of 0.3 mg/mL. Drugs.
Ruxolitinib phosphate
(
HY-50858
), was purchased from
MedChemExpress
.
Pacritinib
was kindly provided by CTI Biopharma.
Real-Time PCR
RNA
(2)
Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants
Cell reports. Medicine
July 15, 2025
Revach OY, Cicerchia AM, Shorer O, Palin CA, Petrova B, Anderson S, Liu B, Park J, Chen L, Mehta A,
et al
.
,
ThermoFisher Scientific
,Cat#
M22426
Hoechst,
Invitrogen
,Cat#
H3570
human
IFNβ,
Peprotech
,Cat#
300-02
Ruxolitinib
JAK
inhibitor
,
MedChemExpress
,Cat#
HY-50858
Human
IFNγ,
R&D Systems
,Cat#
285-IF-100/CF
Zombie
Violet
Dye,
Biolegend
,Cat#
423114
TrueStain FcX,
Biolegend
,Cat#
422302
Mouse
(3)
A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury
Cell reports. Medicine
December 17, 2024
Alexander KA, Tseng HW, Lao HW, Girard D, Barbier V, Ungerer JPJ, McWhinney BC, Samuel SG, Fleming W, Winkler IG,
et al
.
,
Santa Cruz
,"Cat#
sc-203134
, CAS 84371-65-3"
Relacorilant
/CORT125134,ChemieTek,Cat#CT-CORT125
Ruxolitinib
,
MedChemExpress
,Cat#
HY-50858
Indomethacin
,
Selleckchem
,Cat#
S1723
Hypromellose,Merck,Cat#H3785 Peanut oil,Merck,Cat#P2144 TRIzol,
ThermoFisher Scientific
(4)
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
Cancer research
January 18, 2023
Stevens LE, Peluffo G, Qiu X, Temko D, Fassl A, Li Z, Trinh A, Seehawer M, Jovanović B, Alečković M,
et al
.
were started after an overnight
incubation
.
Paclitaxel
(
Sigma
T7191
),
Ruxolitinib
(
MedChemExpress
,
HY50858
),
Solcitinib
(Selleckchem, S5917),
Abrocitinib
(
MedChemExpress
,
HY-107429
),
AZD1480
(
Selleckchem
,
S2162
),
(5)
HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development
Cancer discovery
May 1, 2018
de Bock CE, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O, Vandepoel R, Vicente C, Vanden Bempt M, Dagklis A,
et al
.
(6)
Potential utility of a new ulcerative colitis segmental endoscopic index combining disease severity and the extent of inflammation
Journal of clinical gastroenterology
May 1, 2015
Suzuki Y, Uchiyama K, Kato M, Matsuo K, Nakagawa T, Kishikawa H, Kimura N, Kasanuki J, Ino S.
(7)
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition
Blood
November 21, 2013
Fleischman AG, Maxson JE, Luty SB, Agarwal A, Royer LR, Abel ML, MacManiman JD, Loriaux MM, Druker BJ, Tyner JW.
(8)
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
Blood
April 15, 2010
Quintás-Cardama A, Vaddi K, Liu P, Manshouri T, Li J, Scherle PA, Caulder E, Wen X, Li Y, Waeltz P,
et al
.
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Ruxolitinib phosphate from MedChemExpress
Supplier Page
View Company Product Page
$66.00
Product Specs
Company Info
Citations
Reviews
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