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Protein Biochemistry
Chemicals and Reagents
LS-102
LS-102 from MedChemExpress
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
MedChemExpress for
LS-102
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Description
LS-102 is a selective E3 ubiquitin ligase
synoviolin (Syvn1)
inhibitor. LS-102 inhibits the autoubiquitination of synoviolin with an
IC
50
of 35 µM. LS-102 has the potential for rheumatoid arthritis treatment
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
LS-102
Company
MedChemExpress
Price
$132.00
Supplier Page
View Company Product Page
Catalog Number
HY-135844
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Type
Chemical
Molecular Weight
452.6
Formula
C₂₄H₃₆N₈O
Research Area
Inflammation/Immunology
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (6)
(1)
ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER-Mitochondria Contact Sites
Adv Sci (Weinh)
July 30, 2026
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen
from
Sigma‐Aldrich
. Blasticidin (
S7419
) and
KB‐R7943
(S4643) were obtained from
Selleckchem
.
LS‐102
(
HY‐135844
) was purchased from
MedChemExpress
. 4.2 Antibodies Primary antibodies used were rabbit polyclonal
(2)
HSPA12B Protects Against Age‐Related Endothelial Cell Senescence by Regulating STING Degradation
Aging Cell
October 8, 2025
Tingting Li, Peilin Zhu, Joseph Adams, Fei Tu, Jialing Wang, Chloe Garbe, Suman Dalal, Krishna Singh, Xiaojin Zhang, Li Liu,
et al.
A123995, MOI: 10), C‐176 (STING inhibitor,
MCE
, Cat:
HY‐112906
, 2.5 μM),
LS‐102
(
HRD1
inhibitor
,
MCE
, Cat:
HY‐135844
, 10 μM),
MKC8866
(
XBP1
inhibitor
,
MCE
, Cat:
HY‐104040
, 10 μM),
IXA4
(
MCE
, Cat:
HY‐139214
, 10 μM), siRNA‐control
(3)
Targeting the SYVN1-EGFR axis: a breakthrough strategy for TKI-resistant NSCLC
Cell death & disease
August 28, 2025
Xie X, Tong W, Xie Y, Jiang H, Jiang A, Huang J, Liu Z, Yu J.
hours after
transfection
. MG132 (
HY-13259
), cycloheximide (HY-12320), chloroquine (
HY-17589A
),
LS-102
(
HY-135844
), protease
inhibitor
cocktail (
HY-K0010
), and phosphatase
inhibitor
cocktail (
HY-K0022
) were purchased
(4)
The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
iScience
July 19, 2024
Shi W, Ding R, Chen Y, Ji F, Ji J, Ma W, Jin J.
B6032
Bortezomib
,ApexBio,Cat# A2614 MLN4924,
Boston BioChem
,Cat#
I502-01M
LS-102
,
MedChemExpress
,Cat#
HY-135844
Tunicamycin
,
Cell Signaling Technology
,Cat#
12819
GSK2606414
,
MedChemExpress
,Cat#
HY-18072
Salubrinal
,
MedChemExpress
,Cat#
(5)
Identification of the inhibitory activity of walnut extract on the E3 ligase Syvn1
Molecular medicine reports
December 1, 2018
Fujita H, Aratani S, Yagishita N, Nishioka K, Nakajima T.
(6)
RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis
International journal of molecular medicine
December 1, 2012
Yagishita N, Aratani S, Leach C, Amano T, Yamano Y, Nakatani K, Nishioka K, Nakajima T.
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LS-102 from MedChemExpress
Supplier Page
View Company Product Page
$132.00
Product Specs
Company Info
Citations
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