K858 (Racemic) from MedChemExpress | Biocompare.com

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K858 (Racemic)

Description

K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC₅₀ of 1.3 µM

Product Specs
ItemK858 (Racemic)
CompanyMedChemExpress
Price $55.00Supplier Page View Company Product Page
Catalog NumberHY-19966
Quantity10 mM * 1 mL
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.83%
TypeChemical
Molecular Weight277.34
FormulaC₁₃H₁₅N₃O₂S
Research AreaCancer

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(1) The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cellsInvestigational new drugsAugust 1, 2016De Iuliis F, Taglieri L, Salerno G, Giuffrida A, Milana B, Giantulli S, Carradori S, Silvestri I, Scarpa S.

(2) K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cellsCancer researchMay 1, 2009Nakai R, Iida S, Takahashi T, Tsujita T, Okamoto S, Takada C, Akasaka K, Ichikawa S, Ishida H, Kusaka H, et al.

(3) Hemodynamic effects of prostaglandin E2AnesthesiologyApril 1, 1989Hughes WA, Hughes SC.

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